Views Read Edit View history. Note that the ISS should be used only in people who meet diagnostic criteria for myeloma. Multiple myeloma affects slightly more men than women. Acute kidney failure typically resolves when the calcium and paraprotein levels are brought under control. In , the IMG  agreed on diagnostic criteria for symptomatic myeloma, asymptomatic myeloma, and MGUS, which was subsequently updated in . Pathogens Basel, Switzerland. This suggest that EBV may have a role in the progression of plasmacytomas to systemic multiple myeloma. The diagnostic examination of a person with suspected multiple myeloma typically includes a skeletal survey.
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